.tp-page{font-variant-numeric:tabular-nums;max-width:1240px;margin:0 auto;padding:0 24px 64px}.tp-intro{border-bottom:1px solid var(--line);padding:28px 0 16px}.tp-intro h1{max-width:950px;margin:8px 0 12px;font-size:clamp(1.65rem,3vw,2.45rem);line-height:1.16}.tp-intro p:last-child{color:var(--muted)}#trial-planner{font-size:15px}#trial-planner h2,.tp-method h2{letter-spacing:-.015em;margin:0 0 14px;font-size:1.22rem;line-height:1.3}.tp-toolbar{justify-content:space-between;align-items:center;gap:20px;padding:18px 0;display:flex}.tp-toolbar p{color:var(--ink-soft);margin:0;font-size:.83rem}.tp-workspace{grid-template-columns:minmax(270px,330px) minmax(0,1fr);align-items:start;gap:24px;display:grid}.tp-controls{border:1px solid var(--line);border-radius:var(--radius);background:var(--cloud);padding:22px}.tp-controls fieldset{border:0;border-bottom:1px solid var(--line);min-width:0;margin:0 0 22px;padding:0 0 18px}.tp-controls legend{color:var(--ink);margin-bottom:14px;padding:0;font-size:.92rem;font-weight:700}.tp-field{min-width:0;margin-bottom:12px}#trial-planner label{color:var(--ink);margin-bottom:5px;font-size:.85rem;font-weight:600;display:block}#trial-planner input,#trial-planner select,#trial-planner textarea{width:100%;max-width:100%;min-height:40px;color:var(--text);font:inherit;background:#fff;border:1px solid #96adb9;border-radius:3px;padding:8px 10px;font-size:.9rem}#trial-planner input[readonly]{background:var(--cloud)}#trial-planner input[aria-invalid=true]{border:2px solid #a52f2f}#trial-planner input:focus-visible,#trial-planner select:focus-visible,#trial-planner button:focus-visible,#trial-planner textarea:focus-visible,.tp-scroll:focus-visible{outline:3px solid var(--teal);outline-offset:3px}#trial-planner small,.tp-small{color:#526976;font-size:.8rem;line-height:1.5;display:block}#trial-planner details{margin:14px 0}#trial-planner summary,.tp-method summary{cursor:pointer;color:var(--ink);font-weight:650}#trial-planner details[open]>summary{margin-bottom:14px}.tp-actions{flex-wrap:wrap;align-items:center;gap:8px;display:flex}#trial-planner button{border:1px solid var(--teal);background:var(--teal);color:#fff;cursor:pointer;min-height:40px;font:inherit;border-radius:3px;padding:9px 13px;font-size:.82rem;font-weight:650}#trial-planner button:hover{background:var(--ink);border-color:var(--ink)}#trial-planner button.tp-secondary{color:var(--ink-soft);background:#fff;border-color:#96adb9}#trial-planner button:disabled{cursor:not-allowed;opacity:.48}.tp-output{gap:18px;min-width:0;display:grid}.tp-panel{border:1px solid var(--line);border-radius:var(--radius);background:#fff;min-width:0;padding:22px}.tp-result{border-top:3px solid var(--teal)}.tp-result-top{justify-content:space-between;align-items:start;gap:16px;display:flex}.tp-result-top a{font-size:.8rem}.tp-headline{grid-template-columns:1fr 1fr;gap:20px;margin:18px 0;display:grid}.tp-headline strong{color:var(--ink);letter-spacing:-.035em;font-size:clamp(1.8rem,3vw,2.6rem);font-weight:650;line-height:1.15;display:block}.tp-headline span{color:var(--ink-soft);margin-top:6px;font-size:.8rem;display:block}.tp-result-assumptions{color:var(--muted);font-size:.83rem}#trial-planner table{border-collapse:collapse;width:100%;margin:14px 0;font-size:.82rem}#trial-planner th,#trial-planner td{border-bottom:1px solid var(--line);text-align:right;vertical-align:top;padding:10px 9px}#trial-planner th{color:var(--ink);font-weight:650}#trial-planner th:first-child{text-align:left}.tp-counts th:first-child{max-width:180px}.tp-counts thead th{overflow-wrap:anywhere}.tp-method-id{color:var(--muted);overflow-wrap:anywhere;margin-bottom:0;font-size:.72rem}.tp-error{color:#992424!important}.tp-error:empty{display:none}.tp-stale,.tp-warnings,.tp-mde{color:#59421a;background:#fff8e7;border-left:3px solid #9a6500;padding:10px 12px;font-size:.85rem}.tp-warnings{padding-left:28px}.tp-warnings li+li{margin-top:8px}.tp-scroll{max-width:100%;overflow-x:auto}.tp-comparisons{gap:20px;margin-top:24px;display:grid}.tp-comparisons table{min-width:950px}.tp-comparisons [data-hold]{margin-bottom:12px;max-width:280px!important}.tp-base{background:var(--mist)}#trial-planner .tp-risk-input{width:100px;min-height:36px;padding:5px;font-size:.8rem}#trial-planner .tp-remove{min-height:28px;color:var(--ink);border-color:var(--line);background:#fff;margin-left:6px;padding:0 8px}[data-chart] svg{width:100%;height:auto;display:block}.tp-method{border-top:1px solid var(--line);margin-top:30px;padding-top:24px;font-size:.92rem}.tp-equation{background:var(--cloud);padding:14px;line-height:1.7}.tp-method details{border-bottom:1px solid var(--line);padding:12px 0}.tp-method details p{margin:12px 0 0}.tp-service h2{margin-top:24px}.tp-print-text{display:none}@media (width<=900px){.tp-workspace{grid-template-columns:minmax(240px,280px) minmax(0,1fr);gap:16px}.tp-controls,.tp-panel{padding:16px}.tp-result-top{flex-wrap:wrap}}@media (width<=700px){.tp-page{padding-inline:16px}.tp-workspace{grid-template-columns:minmax(0,1fr)}.tp-toolbar{align-items:start}.tp-panel{padding:16px}.tp-headline{gap:10px}.tp-result-top{display:block}.tp-result-top button{margin-bottom:12px}.tp-counts th,.tp-counts td{padding:9px 5px!important}.tp-intro h1{font-size:1.75rem}}@media print{.site-header,.site-footer,.tp-controls,.tp-toolbar,.tp-export,.tp-service,.preview-banner,.tp-comparisons,.tp-method{display:none!important}.tp-workspace{display:block}.tp-page{max-width:none;padding:0}.tp-panel{break-inside:avoid;margin-bottom:15px}.tp-scroll{overflow:visible}.tp-print-text{white-space:pre-wrap;overflow-wrap:anywhere;font-family:inherit;font-size:10pt;display:block}}
/*$vite$:1*/